After a challenging start to 2021, the global box office reignited with the stunning success of Spider-Man: No Way Home, which is still swinging away.

The latest Spider-Man movie is currently up to a massive $1.62 billion, making it the eighth biggest movie of all time. While it was always going to be a hit, No Way Home's mega haul is something that many didn't think was going to be possible with cinemagoing still not quite back to 'normal'.

Its success has renewed belief that we could get back to regular $1 billion hits at the box office. We might not get nine of them, as we did in an unprecedented 2019, but there's hope that No Way Home isn't just an anomaly, with plenty of blockbuster potential to come in 2022.

So what could actually be the biggest box-office hit of 2022? There might be three Marvel movies on the way, but we actually think the year's highest-grossing movie might come from outside of the MCU.

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Let's start by looking at the Marvel contenders in 2022, not including Morbius (sorry Jared Leto).

We've got three MCU movies heading our way this year if the release dates stay the same: Doctor Strange in the Multiverse of Madness (May 6), Thor: Love and Thunder (July 8) and Black Panther: Wakanda Forever (November 11).

Of those, the Black Panther sequel looks most likely to hit $1 billion, given the first movie made a tremendous $1.34 billion worldwide. That outing was a cultural event and anticipation will be equally high for the sequel, especially in terms of how it will pay tribute to the late Chadwick Boseman.

Doctor Strange 2 might get a Spider-Man boost, but the character doesn't appear to be one of the most beloved in the MCU. The first movie 'only' took $676.4 million worldwide and while MCU sequels have generally seen a boost in numbers, it remains to be seen if the multiversal madness can be as much of a draw as it was for No Way Home.